Healthy Living

Helpful Tips You Can Use to Boost Your Immunity – Indonesia Expat

  • December 31, 2020

Many supplements and products in the market claim to boost your immunity.

While it may sound like a no-brainer, taking the necessary steps to make your body’s immune system stronger is more complicated than you think. Your immune system is complicated and has to be healthy and smart enough to fight all types of infections and diseases. Now that the world is suffering from the pandemic, it’s imperative to increase your body’s immune system to fight the coronavirus.

There’s a way to ensure that your immune system is healthy, and that’s by changing your lifestyle and your day to day activities. From taking the right food and supplements to getting enough exercise, read on to learn some useful tips for boosting your immunity.

Exercise.

Physical activity is good for your body for various reasons. It doesn’t only help build muscles, but it also enables you to destress and boost your body’s immune system. When you exercise, you increase your body’s circulation. This makes it easier for your immune cells and other infection-fighting molecules to travel freely throughout your body.

Drink plenty of water.

You’ve probably heard that drinking over two liters per day is essential. Water plays a vital role in your body, which includes supporting your body’s immunity. There’s a particular fluid in your circulatory system that’s called the lymphatic fluid. The lymphatic fluid carries essential infection-fighting immune cells through your entire body and is mostly made of water. If you lack enough water in your body and are dehydrated, it will slow the lymphatic fluid movement, harming your body’s immune system.

Even when you’re not exercising and sweating, your body still loses water when you breathe or use the restroom. To help support a robust immune system, ensure you replace the water you’re losing every day by drinking six to eight glasses of water per day.

Take the right supplements.

There are specific supplements you can take that can help boost your immunity. If you currently don’t use any supplements, now may be the time to consider purchasing some and adding them to your daily routine.

Other than supplements like vitamin C, you can also take CBD supplements to reduce inflammation and boost your immunity. They come in many forms available in the market. You can also purchase wholesale CBD gummies and add them to your routine.

Get enough sleep.

Sleep is a regenerative process that’s crucial for your body. Sleep is a necessary time when your body repairs, reprocesses and rebuilds your cells. When you lack sleep, your T cells or natural immune cells decrease, and inflammatory cells increase. T cells contribute to your body’s immune response when a potentially harmful foreign body enters your system. The immune cells recognize the pathogens and then release integrin, a protein that allows T cells to attach and fight foreign substances.

Enough sleep also helps the body get better faster after falling sick.

Best Foods to Prevent a Cold, According to Doctors

Best Foods to Prevent a Cold, According to Doctors

  • December 31, 2020

During those months when the temperature drops, more people start to suffer from the common cold. While catching a cold is more of an annoyance than anything else, when you’re living in the midst of a pandemic, you want to make sure you’re staying as healthy as possible. So that means doing all you can to avoid a pesky cold. And that starts in your kitchen.

The foods you eat can play a big role, as you want to make sure your diet is filled with immune-boosting foods.

“Eating a healthy diet helps ensure that your immune system is strong enough to fight off infections,” says Cedrina Calder, MD MSPH, a preventive medicine doctor in Nashville, Tennessee. “Certain nutrients play an important role in a healthy immune response.”

So one food isn’t just going to magically prevent you from ever getting sick again, but loading up on foods with essential nutrients will keep you on the right path, hopefully away from catching any colds.

“If you want to boost your immune system’s resilience, you need to move from a stress eating diet, to an acid-kicking strength eating diet,” says Dr. Daryl Gioffre, nutritionist and author of Get Off Your Acid and Get Off Your Sugar. “A strength eating lifestyle is based on adding low acid, high alkaline plant-based foods that help you gain energy, lose weight, and lower the inflammation levels in your body.”

To help you out, here’s a full list of the best types of nutrients and foods that best prevent you from catching a cold. While you’re making healthier choices, be sure to try out any of The 7 Healthiest Foods to Eat Right Now.

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“Vitamin A plays a significant role in fighting infections,” says Calder. “Great sources of vitamin A include foods with orange-colored flesh like sweet potatoes, carrots, and squash. In addition, vegetables like spinach and broccoli are also packed with vitamin A.”

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“Sprouts are baby versions of the vegetables they grow into, and they are undeniable superfoods,” says Gioffre. “Sprouts are also jam-packed with nutrients, particularly sulforaphane and isothiocyanate—two compounds that have demonstrated immune-boosting anti-cancer properties. Along with boosting immune function, broccoli sprouts are also loaded with antioxidants, such as glucoraphanin, that help your body fight off illnesses. In fact, these sprouts are the number one cancer-fighting food you can put into your body, because of their ability to boost immune function and strengthen your resilience. A general rule of thumb is that sprouts have thirty times the nutrition of the fully grown version of that vegetable.”

Go ahead and pile them on top of your salad! Gioffre suggests “using them in lieu of lettuce altogether” if you’re feeling adventurous.

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Vitamin C serves as an antioxidant and stimulates immune cells,” explains Calder. “Some of the best sources of vitamin C include bell peppers, broccoli, citrus fruits, and berries.”

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“Because watercress is an extremely low-calorie yet vitamin- and mineral-rich food, it is highly nutrient-dense. In fact, it ranks as the most nutrient-dense food on the CDC’s Powerhouse Fruits and Vegetables list, in part thanks to its concentration of minerals, including magnesium, calcium, manganese, and potassium, along with vitamins A, C, and K,” Gioffre explains. “Like the other cruciferous vegetables, it’s rich in free radical–neutralizing antioxidants that strengthen your cells and protect your immune system.”

Treat it as you would any other leafy green—toss it “in salads, sandwiches, smoothies, and sautés,” Gioffre says.

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Vitamin D serves an important role in immune function but [a] deficiency in vitamin D is very common,” Calder explains. “To help meet your vitamin D needs, incorporate foods like fatty fish including salmon, tuna, and mackerel into your diet.”

Looking for more helpful tips? Sign up for our newsletter to get daily recipes and food news in your inbox!

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“Celery is mostly water and incredibly hydrating, yet high in soluble and insoluble fiber and mineral content,” Gioffre says. “Indeed, it contains an array of minerals essential to a healthy immune system, that also help neutralize acids and toxins that make you more vulnerable. Celery also contains anti-inflammatory compounds that can help dampen that internal fire throughout the body that ultimately suppresses immune function, thus reducing risk of infection and disease.”

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Vitamin E is another antioxidant that helps regulate the immune system,” Calder says. “Nuts, seeds, and oils like almonds, hazelnuts, sunflower oil, and sunflower seeds provide a good amount of vitamin E.”

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Avocados are a good source of Glutathione—a powerful antioxidant associated with immune system health, needed for the lymphoid cells,” Gioffre says. “Avocados also contain vitamins A, C, and E, which are antioxidants that strengthen your immune system. It literally is the perfect immune-boosting and protecting food.”

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Zinc is a mineral that is necessary for the development and function of immune cells,” Calder says. “If you’re a seafood lover you’re in luck because oysters contain more zinc than any other food. Crab and lobster are also good sources.”

Any excuse to eat more lobster, right?

Doctor Discusses Supplements to Consider and Avoid

Doctor Discusses Supplements to Consider and Avoid

  • December 31, 2020

CHARLOTTE, N.C. — While most Americans are waiting their turn to get vaccinated against COVID-19, some people are turning to supplements to prevent getting the virus.


What You Need To Know

  • Vitamin C, vitamin D, and Zinc are showing promising results in the prevention of COVID-19
  • Dr. Russell Greenfield from Novant Health said the best tools to prevent the virus are hand washing, social distancing, masking, and getting adequate sleep
  • If you are considering taking supplements, Greenfield said you should ask doctors or pharmacists for recommended amounts

Supplements that boost the immune system are in high demand at Charlotte Vitamins and Health.

“Vitamin D has been very popular. Very hard to keep on the shelf,” Owner Brian Peterson says.

He adds that vitamin C and zinc have also been top sellers amid the pandemic.

“I don’t know if I’m surprised. There is a lot of fear. They are looking for any way they can improve their health,” Peterson says.

Early research found these supplements may help prevent COVID-19.

For example, early research findings suggest people with normal vitamin D levels have a lower risk of contracting the virus.

“It appears if people have low vitamin D levels, they may be at more risk, and they may be actually at risk for severe disease,” Novant Health’s Director of Integrative Medicine Dr. Russell Greenfield says.

He added while vitamin D, vitamin C, and zinc supplements may be beneficial when it comes to COVID-19, he needs more research to say they are a must.

“We say it looks promising, and if in your unique circumstances it’s safe to use these agents, supplementation may be a good idea,” Greenfield says.

However, he said there are supplements he is not recommending.

“I would ask people to stay away from agents that contain or primarily use colloidal silver, because it doesn’t have any significant benefit that we can tell, and when people take this for a long period of time or in high doses, they can develop a blue discoloration of the skin that doesn’t go away,” Greenfield says.

He recommends holding off on taking elderberry products because he says it’s unknown if they are safe in preventing COVID-19.

Greenfield says while some supplements may help prevent COVID-19, the most important tools are at our disposal to stay safe, include social distancing, hand washing, wearing masks, and getting adequate sleep.

If you plan to take supplements, Greenfield says you should check with your doctor or pharmacist first for recommended amounts. 

Health and Fitness: Exercise is one of the best ways to boost immunity - Albert Lea Tribune

Health and Fitness: Exercise is one of the best ways to boost immunity – Albert Lea Tribune

  • December 30, 2020

Health and Fitness by Mollee Tscholl

The immune system is defined as a complex network of biological structures and processes within an organism that protects it against disease. As human beings, having a healthy immune system is critical to our ability to combat illness and fight off diseases. Right now, caught in the middle of a pandemic, in which our bodies are waging war against a brand new adversary — COVID-19 — the need for strong immune systems is more important than ever. The CDC and MDH continue to promote mask-wearing and social distancing as a means of warring off COVID-19, but while these things help protect us from exposure, they don’t help strengthen the immune system. What, then, can we be doing to prepare our bodies to put up a good fight, should the virus or another illness or disease find us and want to do battle?

Mollee Tscholl

Believe it or not, one of the best things we can do is get regular exercise! As a gym owner, trainer and long-time exercise enthusiast, this is perhaps one of the biggest reasons it was hard to stomach Governor Walz’s most recent executive order, again, closing down fitness centers in Minnesota, at the start of the winter season no less. Looking specifically at COVID-19, it’s estimated that 20% to 42% of hospitalized patients will develop Acute Respiratory Distress Syndrome (ARDS); for patients admitted to intensive care, this range increases to 67% to 85%. A recent review, however, by Zhen Yan of the University of Virginia School of Medicine found medical research findings to “strongly support” the possibility that exercise can prevent or at least reduce the severity of Acute Respiratory Distress Syndrome. The production of an antioxidant called Extracellular Superoxide Dismutase (EcSoD), which is naturally produced in our muscles, and works by hunting down harmful free radicals, is known to increase with cardiovascular exercise. EcSoD, has been found to be deficient in patients who have not only acute lung disease, but also those who have ischemic heart disease, kidney failure and osteoarthritis. So, in short, regular exercise, can help our bodies fight off or at the least, reduce the severity of COVID-19 and other various illnesses and diseases.

Stress, a common cause of a weakened immune system, is high right now due to all of the changes and restrictions we are facing from this pandemic. The good news is stress can also be combated through exercise! Chemicals called endorphins, which are produced by the body to combat stress and pain, are released into the body during exercise. At the same time, cortisol, the body’s stress hormone, is lowered through exercise. So, remember, during stressful times, exercise can be a game-changer in keeping you physically and mentally strong. Get that sweat on! Move that body! 

A few other things you can do to strengthen your immune system are getting an adequate night’s sleep, eating a diet rich in fruits and vegetables and/or taking a multi-vitamin, and maintaining social connection with others. So, in a time where social gatherings are discouraged, make those phone calls, schedule those Zoom meetings, write that long put-off letter you’ve been meaning to send!

We at SNAP Fitness wish you all a happy and healthy 2021, one in which we can soon get back to doing the things and seeing the people we love!

Mollee Tscholl is co-owner of Albert Lea’s SNAP Fitness and TMJ Elite Fitness.

How the Sinopharm Covid-19 Vaccine Works

How the Sinopharm Covid-19 Vaccine Works

  • December 30, 2020








In early 2020, the Beijing Institute of Biological Products created an inactivated coronavirus vaccine called BBIBP-CorV. It was later put into clinical trials by the state-owned Chinese company Sinopharm. On Dec. 30, Sinopharm announced that the vaccine had an efficacy of 79.34 percent. The vaccine is now in use in Bahrain and the United Arab Emirates. Sinopharm has also applied to the Chinese government for approval.

A Vaccine Made From Coronaviruses

BBIBP-CorV works by teaching the immune system to make antibodies against the SARS-CoV-2 coronavirus. The antibodies attach to viral proteins, such as the so-called spike proteins that stud its surface.







To create BBIBP-CorV, the Beijing Institute researchers obtained three variants of the coronavirus from patients in Chinese hospitals. They picked one of the variants because it was able to multiply quickly in monkey kidney cells grown in bioreactor tanks.

Killing the Virus

Once the researchers produced large stocks of the coronaviruses, they doused them with a chemical called beta-propiolactone. The compound disabled the coronaviruses by bonding to their genes. The inactivated coronaviruses could no longer replicate. But their proteins, including spike, remained intact.







The researchers then drew off the inactivated viruses and mixed them with a tiny amount of an aluminum-based compound called an adjuvant. Adjuvants stimulate the immune system to boost its response to a vaccine.

Inactivated viruses have been used for over a century. Jonas Salk used them to create his polio vaccine in the 1950s, and they’re the bases for vaccines against other diseases including rabies and hepatitis A.

Prompting an Immune Response

Because the coronaviruses in BBIBP-CorV are dead, they can be injected into the arm without causing Covid-19. Once inside the body, some of the inactivated viruses are swallowed up by a type of immune cell called an antigen-presenting cell.






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The antigen-presenting cell tears the coronavirus apart and displays some of its fragments on its surface. A so-called helper T cell may detect the fragment. If the fragment fits into one of its surface proteins, the T cell becomes activated and can help recruit other immune cells to respond to the vaccine.

Making Antibodies

Another type of immune cell, called a B cell, may also encounter the inactivated coronavirus. B cells have surface proteins in a huge variety of shapes, and a few might have the right shape to latch onto the coronavirus. When a B cell locks on, it can pull part or all of the virus inside and present coronavirus fragments on its surface.

A helper T cell activated against the coronavirus can latch onto the same fragment. When that happens, the B cell gets activated, too. It proliferates and pours out antibodies that have the same shape as their surface proteins.






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Stopping the Virus

Once vaccinated with BBIBP-CorV, the immune system can respond to an infection of live coronaviruses. B cells produce antibodies that stick to the invaders. Antibodies that target the spike protein can prevent the virus from entering cells. Other kinds of antibodies may block the virus by other means.


Remembering the Virus

Sinopharm’s clinical trials have demonstrated that BBIBP-CorV can protect people against Covid-19. But no one can yet say how long that protection lasts. It’s possible that the level of antibodies drops over the course of months. But the immune system also contains special cells called memory B cells that might retain information about the coronavirus for years or even decades.

Vaccine Timeline

January, 2020 Sinopharm begins developing an inactivated vaccine against the coronavirus.

June Researchers report the vaccine produces promising results in monkeys. A Phase 1/2 trial shows that the vaccine doesn’t cause any serious side effects and enables people to make antibodies against the coronavirus.



A Sinopharm production plant in Beijing.Zhang Yuwei/Xinhua, via Associated Press

July A Phase 3 trial begins in the United Arab Emirates.

August Phase 3 trials begin in Morocco and Peru.



Preparing a Sinopharm dose in Lima, Peru.Ernesto Benavides/Agence France-Presse

Sept. 14 The U.A.E. gives emergency approval for Sinopharm’s vaccine to use on health care workers. Government officials and others begin to receive it.

November The chairman of Sinopharm says almost a million people in China have received Sinopharm vaccines.

Nov. 3 The ruler of Dubai, Sheikh Mohammed bin Rashid al-Maktoum, announces he received the vaccine.



Sheikh Mohammed before receiving the vaccine.Agence France-Presse

Dec. 9 The U.A.E. gives full approval to BBIBP-CorV, announcing it has an efficacy rate of 86 percent. But the government did not release any details with their announcement, leaving it unclear how they had come to their conclusions.

Dec. 13 Bahrain also approves the vaccine.



Vials of the Sinopharm vaccine at a packaging plant.Zhang Yuwei/Xinhua, via Associated Press

Dec. 30 Sinopharm announces that the vaccine has an efficacy of 79.34 percent. The company has yet to publish the detailed results of their Phase 3 trial.


Sources: National Center for Biotechnology Information; Science; The Lancet; Lynda Coughlan, University of Maryland School of Medicine; Jenna Guthmiller, University of Chicago.

Tracking the Coronavirus


Intercepting Lung Cancer Could be More than Just a Dream

Intercepting Lung Cancer Could be More than Just a Dream

  • December 30, 2020

The results of the National Lung Screening Trial (NLST) shifted what was known to be possible in lung cancer diagnostics.

The National Cancer Institute-funded research, published originally in August 2011, showed low-dose computed tomography (CT) scanning for high-risk patients could provide a relative 20% reduction in mortality risk from lung cancer versus standard radiography.

At the time, multi-detector CT was theorized to make high-resolution volumetric imaging possible through just a single breath, Denise R. Aberle, MD, and colleagues wrote.

Though the results provided an affirmative answer that, yes, low-dose CT screening is more beneficial than chest radiography in reducing risk of death from lung cancer before a patient is even diagnosed—in just 3 rounds of screening.

But it more importantly set questions to answer in the pursuit of this new paradigm:

  • What is the optimal screening program?
  • Could NLST be over-diagnosing non-symptomatic cancers?
  • In a world filled with current and former smokers, what is appropriate eligibility criteria?
  • Is this even cost-effective?

Aberle and colleagues even concluded on a question: could biomarkers in blood, sputum, and urine help identify low-dose CT screening patients?

Namely, is there an earlier level by which clinicians can predict who is at risk of the deadliest cancer in the world?

The NLST research team’s work generated change. The US adopted screening practices including CT scans that would be covered by Medicare. Millions suddenly had access to a window of better interpreted lung cancer risks. But the questions raised by the study investigators remained unanswered.

Steven Dubinett, MD, was among those to see a challenge among the trial results. The director of the UCLA Clinical & Translational Science Institute and a colleague of Aberle told HCPLive® that only a “fraction” of patients who should be or are eligible for screening are actually doing so.

“As these screening programs roll out in the US, we need to actually decide how we will actually improve screening to make it more accurate,” Dubinett said. “And part of that is to understand how lung cancer develops, and really understand how we might be able to use additional biomarkers to help us make the diagnosis.”

Ten years ago, investigators learned to spot lung cancer risk. Now, they wish to intercept it altogether.

A Growing Challenge

What Dubinett sees is incremental successes backdropped against rapidly growing problems. Through the diagnostic advancements of his peers like Alberne, and through therapeutic innovation, the five-year survival rate of lung cancer in the US has improved from 13% to 18%. At the same time, a lesser rate of the population is smoking combustible cigarettes—one of the greatest known drivers of lung cancer risk.

Globally, though, the situation worsens. A ten-year observation of worldwide lung cancer cases ending in 2018 found there is about 2 million new cases annually—and nearly just as many deaths. Lung cancer has increased by nearly 40% worldwide in a decade, Dubinett said.

What’s more, nearly half of all newly diagnosed patients are in advanced stages and unamenable to possibly life-saving surgeries—still the optimal method of lung cancer care.

Lung cancer interception, in theory, would grant clinicians the confidence to streamline the most at-risk patients to invasive care before even a symptom could occur—treating stage 1 patients rather than stage 4. Its foundation is set by the low-dose CT scan benefits observed by the NLST team, and its potential could mean complete prevention of lung cancer progression.

Dubinett currently serves as co-leader of the Lung Cancer Interception Dream Team, a multi-million figure-funded national research team supported the American Lung Association (ALA), Stand Up 2 Cancer (SU2C), and the LUNGevity Foundation.

The team, led by Avrum Spira, MD, Professor of Medicine, Pathology and Bioinformatics, and the Alexander Graham Bell Professor in Health Care Entrepreneurship at Boston University, has been seeking diagnostic breakthroughs that would differentiate guidance on chest scans and establish greater confidence in observed lung cancer risk in a patients’ tissues.

As Spira told HCPLive in an episode of Lungcast earlier this year, the team is aiming to understand the very first cellular molecular changes which lead to the development of precancerous tissues in at-risk patients. This gap of knowledge is integral to their overall goal of intercepting the deadliest cancer in the world.

“Those findings are going to provide insights into novel targets that we can go after to intercept someone before they develop fully-blown lung cancer,” Spira said.

Finding Step One

Where experts like Dubinett are currently fixed is in the pre-malignant lesions of would-be patient’s tissues: what makes them abnormal? How does it lead to cancer?

The dream team is sequencing the information collected from pre-malignant lesions to define DNA, RNA, and cellular phenotypes. Spira described the final work as an “atlas” of both squamous cell and adenocarcinoma, the 2 most common cancer subtypes.

“The concept here is to put together very unique cohorts of patients that have pre-cancerous lesions in their airway or lung and are being followed over time, to see whether those lesions progress onto invasive cancer, and study those lesions with the best molecular profiling tools we have available,” Spira said.

The greatest challenge in this venture, Dubinett explained, is the occult status of tissues with pre-malignant lesions. Unlike other cancers, lung cancer does not have a currently-understood clinical pathway which allows researchers to find these specimens—Dubinett, Spira, and their peers have to blaze the trail.

“These abnormal cells in the lung provoke our immune systems to attack the cells,” Dubinett explained. “And at the same time, those abnormal areas of pre-malignancy that become invasive have an immune suppression happening within the area of the abnormality.”

In layman’s terms, investigators now understand that the balance of immunity—when the body turns on immune response to attack bacteria or viruses—is compromised by abnormal cells which becomes cancerous. As such, it is difficult for Dubinett and colleagues to distinguish the “foreignness of cancer cells” from the immune system itself.

Through funding and time, the teams have begun to uncover the trail.

In beginning to interpret the immune deficits driven by the abnormal cancer cells, clinicians may be able to pinpoint timely opportunities to aid the immune system prior to invasive care which would significantly reduce the burden of a cancerous tumor. Such research is already underway.

“And that suggests to us, in fact, that in the early stages of lung cancer, before the immune system becomes fully depressed, we have this opportunity to really go after the tumor cells, boost the immune system, and have the patient’s own body help and be involved in destroying those abnormal cells,” Dubinett explained.

A Future of Interception

Dubinett endorses the idea that the future of medicine is dictated by the research being done today. Laboratory-based trials, fixed on the very fundamental pathology of disease, can improve the aim of clinical trials, improve the standard of care, and help set models for efficient clinical practice.

It’s that mindset which explains why the work of Aberle and the NLST research team was integral to the current opportunities of the Interception Dream Team. That mindset also evidences the need for more lung cancer screening via CT scans—a practice evidenced by foundational research, which could only advance such research even further.

Primary research is only half the puzzle, of course. Financial backing from invested institutions including the ALA, LUNGevity, and SU2C are integral to the right discoveries being made in due time. Dubinett called on federal and state agencies to continue their support of cancer research which aims to uncover preventive care outcomes.

Today’s ideas of lung cancer interception are feeding screening, diagnostic, and immunotherapy studies of the coming years, racing against a growing wave of global lung cancer cases and deaths.

The individual patient it may save could be a post-surgery patient with ill-defined patterns on their CT scan. They may have benefitted from an innovative PET scan, or were monitored with a new-wave bronchoscopy device that can find Dubinett’s and Spira’s found areas of abnormalities. They may be a smoker, or not. They may be older, or surprisingly young. But what they must be is early-stage—afforded enough time to make a difference in their would-be disease.

“This might be individuals who, for example, are in screening programs, who have a heavy smoking history, and are being monitored in annual CT scans. It could be patients following surgery for lung cancer,” Dubinett said. “This is a way that we could really make progress toward really effective interception, that makes a profound change in what we’re able to accomplish for patients with lung cancer—that is, preventing them from actually having it.”

The research being done today to understand millions of new cases could direct the therapeutic decisions which eventually save as many lives.

Health Addiction’s Functional Supplements Part of 2021 Health Trends

Health Addiction’s Functional Supplements Part of 2021 Health Trends

  • December 30, 2020

PALM BEACH, FL, Dec. 30, 2020 (GLOBE NEWSWIRE) — Functional nutrition is about to get more popular in 2021.

Healthline.com reported that Americans’ priorities have changed with a new focus on health and well-being.

The health and wellness website listed “functional nutrition” as the number one health trend for 2021.

“It is nice to know the rest of the world is catching up to us. At Health Addiction, we have been developing functional nutritional supplements for years,” said Nathaly Marcus, founder and functional nutritionist for Health Addiction, a wellness company in Mexico City. 

Healthline reports that more than 50 percent of consumers are taking more supplements, specifically to improve their immune system.

“Functional nutrition takes a holistic approach to overall health,” Ms. Marcus said. “At Health Addiction, our supplements target vital areas of your health, including the gut, immune system, cardiovascular health, and joints,

Health Addiction’s functional supplements that will be available in the U.S. are:

  • ESSENTIAL 5 addresses the five most important health pillars: nervous system, gut health, immune system, and cardiovascular system. It also provides an energy boost.
  • GLOW PACK helps regenerate and build healthy, radiant skin, hair and nails.
  • PRE + PROBIOTIC COMPLETE FORMULA helps regenerate the gut system and support the immune system.
  • THERMO BURN MAX is a unique fat burner formula for weight loss.
  • GUT BALANCE optimizes gut function, decreases gut inflammation, and improves nutrient absorption.
  • SPORT COLLAGEN BOOSTER promotes ligament and joint elasticity and structure.
  • SPIRULINA + CHLORELLA + MORINGA COMPLEX helps detoxify the body, support the immune system, and promote cell regeneration.
  • GASTRO 360 optimizes proper gut function and aids in heartburn, colitis, nausea and, acid reflux problems.

“I learned years ago that holistic medicine and functional nutrition improved peoples’ lives,” Ms. Marcus said. “Now, because of the worst pandemic in more than 100 years, people are prioritizing their health more than ever before.”

For more information, please visit Health Addiction online.

 

Robert Grant
Health Addiction
(561) 421-3045
pr@nutrapr.com

Taking Melatonin Could Help Prevent COVID, New Study Says

Taking Melatonin Could Help Prevent COVID, New Study Says

  • December 30, 2020
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On a day-to-day basis, keeping COVID at bay typically comes down to the U.S. Center for Disease Control and Prevention’s (CDC) golden rules: wearing a face mask, social distancing, and regularly washing or sanitizing your hands. But as the pandemic has progressed, scientists have done more research to gain a better understanding of different ways to treat or lessen the risk of infection, including certain vitamins that could give your body a defense boost. Now, a new study published in the journal PLOS Biology has found that you can add melatonin to the list of supplements that could help prevent COVID. Read on to see what melatonin can do for you, and for what you don’t need to be doing to keep yourself safe, check out The One Thing You Can Stop Doing to Avoid COVID, According to Doctors.

Through the use of artificial intelligence, researchers at the Cleveland Clinic were able to sort through data on over 27,000 patients in a COVID-19 registry to find any commonalities. Interestingly, results showed that those who regularly took the sleep hormone melatonin were about 28 percent less likely to test positive for COVID—with Black patients showing an even greater reduced likelihood of 52 percent.

“When we got this result, we were very excited,” Feixiong Cheng, PhD, lead researcher from the Cleveland Clinic’s Genomic Medicine Institute, told local CBS affiliate KIRO 7. “If our findings can help the patients, that’s our goal and mission—and at the Cleveland Clinic as well.”

The researchers admit that they don’t entirely understand what “exact mechanisms” about melatonin provide extra protection against COVID, including whether or not it’s because patients are sleeping better, longer hours, the New York Post reports. And Cheng and his team also cautioned people against filling up on melatonin based on the study’s results. “It is very important to note these findings do not suggest people should start to take melatonin without consulting their physician,” Cheng said in a November statement upon the study’s release. “Large-scale observational studies and randomized controlled trials are critical to validate the clinical benefit of melatonin for patients with COVID-19, but we are excited about the associations put forth in this study and the opportunity to further explore them.”

Despite that cautiously optimistic stance, other research has found that melatonin may do more than just prevent COVID, too. A recent study from the University of Toronto published in the journal Diseases found that melatonin could help boost the efficacy of the coronavirus vaccine, calling it a potential “silver bullet” in the fight against the pandemic.

But melatonin isn’t the only supplement shown to be potentially effective in fighting COVID. Read on to see what else studies have found in regards to supplements that can help you fight off the virus. And for more on the latest COVID news, check out The New COVID Strain Is in the U.S. and It’s Bad News for 2 Reasons.

Read the original article on Best Life.

ealthy product sources of zinc, including chicken, liver, shellfish, and eggs
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If you ever need an excuse to take advantage of an oyster dinner, this might just be it. A Spanish study from March and April found that patients who had higher levels of zinc in their blood were more likely to survive the disease than those who had much lower levels.

“It has long been thought that zinc bolsters the immune system,” Len Horovitz, MD, a pulmonologist at Lenox Hill Hospital in New York City, told WebMD. “A possible explanation in this study is that zinc may have an anti-inflammatory effect that is protective.” And for more ways to keep the coronavirus out of your house, check out If You Don’t Have This in Your Home, You’re at Higher Risk for COVID.

Vitamin D Supplements
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When it comes to protection against the virus, there’s mounting evidence that vitamin D can play a huge part in keeping you safe from even getting sick. One study, published in September in the Journal of the American Medical Association, found that having a vitamin D deficiency increases your risk of testing positive for the coronavirus by nearly 80 percent.

Even Anthony Fauci, MD, agrees with the findings. “If you’re deficient in vitamin D, that does have an impact on your susceptibility to infection. I would not mind recommending—and I do it myself—taking vitamin D supplements,” he said during an Instagram Live interview with actor Jennifer Garner in September. And for more on how COVID will affect you if you do get sick, check out This One Thing Could Determine If Your COVID Case Will Be Severe or Mild.

Foods High in vitamin C on a wooden board, including oranges, almonds, kiwis, bananas, peppers, and more
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Vitamin C is well known for boosting your immune system, but it could also be helpful in keeping you safe from COVID. According to researchers at Augusta University in Georgia, a meta-analysis of more than 30 other studies on the long-trumpeted immune-boosting effects of vitamin C shows that it appears to be lacking in many patients who develop serious cases of COVID-19.

It’s also important to remember that you can get your daily dose of vitamin C without making a trip to the supplement aisle. Loading up on citrus fruits, tomatoes, leafy greens, peppers, and more can help you stave off COVID and other ailments, including the flu and common colds. And for more regular updates on the pandemic, sign up for our daily newsletter.

Foods Highest in Vitamin B1 (Thiamin)- top view
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While vitamin B has not been proven to have a direct effect on coronavirus, it’s widely known that it does a lot to help keep your immune system in great shape. One study on the link between COVID and vitamin B found that it “assists in proper activation of both the innate and adaptive immune responses, reduces pro-inflammatory cytokine levels, improves respiratory function, maintains endothelial integrity, prevents hypercoagulability and can reduce the length of stay in hospital.” Because of this, the study suggests that a COVID patient’s vitamin B levels should be assessed along with their vitamin D status. And for more on what could lead to a bad case of the coronavirus, check out If You Have This Blood Type, You’re at a High Risk of Severe COVID.

Therapeutic Solutions International Reports QuadraMune™ Increases T Cell Immunity in Animal Studies

  • December 30, 2020

OCEANSIDE, Calif., Dec. 30, 2020 /PRNewswire/ — Therapeutic Solutions International, Inc., (OTC Markets: TSOI), reported today new data demonstrating a two-week course of QuadraMune™ increased immunological parameters relevant to antiviral immunity. 

In a series of experiments, the Company demonstrated that animals injected with a model antigen, keyhole limpet hemacyanin (KLH) possessed a significantly enhanced T cell response.  The type of T cell response that was preferentially elicited in animals taking QuadraMune was associated with interferon gamma, a protein known to inhibit viral replication.

“Previously we have demonstrated that QuadraMune is associated with enhanced natural killer cells, which represent the innate arm of the immune system” said Dr. James Veltmeyer, Chief Medical Officer of the Company. “The demonstration that the adaptive immune response is also enhanced by QuadraMune, provides further rationale for evaluation of this nutraceutical as a preventative for COVID-19.”

The Company is currently running a clinical trial in health care workers using QuadraMune to prevent COVID-19 infection.  More information on the clinical trial can be found on the Federal Clinical Trials registry as #NCT04421391.

“Although there are numerous nutraceutical products on the market that claim to boost immunity, I am extremely proud that we as a company are differentiating ourselves by conducting scientific experiments to objectively validate our approach” said Famela Ramos, Vice President of Business Development.

“Our Company is based on utilizing the immune system to treat numerous chronic and degenerative conditions.  Today’s findings, that QuadraMune stimulates the Th1 arm of the immune system, suggests that QuadraMune may be useful for other conditions associated with immune dysregulation” said Timothy Dixon, President and CEO of the Company. “It is believed that Th1 immunity is useful not only in the treatment of viruses but also in eradication of cancer and intracellular bacterial.”

About Therapeutic Solutions International, Inc.
Therapeutic Solutions International is focused on immune modulation for the treatment of several specific diseases. The Company’s corporate website is www.therapeuticsolutionsint.com, and our public forum is https://board.therapeuticsolutionsint.com/ and Campbell Neurosciences at https://www.campbellneurosciences.com

[email protected]

SOURCE Therapeutic Solutions International

Related Links

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CEL-SCI Reports Fiscal 2020 Financial Results and Clinical & Corporate Developments

  • December 30, 2020

Dec. 30, 2020 13:00 UTC

VIENNA, Va.–(BUSINESS WIRE)– CEL-SCI Corporation (NYSE American: CVM) reported financial results for the fiscal year ended September 30, 2020, as well as key clinical and corporate developments.

Clinical and Corporate Developments included:

  • During fiscal 2020, the Independent Data Monitoring Committee (IDMC) for the Company’s pivotal Phase 3 head and neck cancer study of Multikine* (Leukocyte Interleukin, Injection) conducted an official review of the study data in October 2019 and April 2020, and recommended in each case that the trial continue until the appropriate number of events has occurred. CEL-SCI announced in early May 2020 that the study reached the targeted threshold of 298 events (deaths) required to conduct the data evaluation and the process of data lock commenced. In December 2020, the study entered its final stage of statistical analysis of all study data.

  • In preparation for potential marketing clearance, CEL-SCI began expanding and upgrading its dedicated cGMP facility in which it manufactures Multikine. The construction will double the facility’s capacity, accommodating two shifts for increased production of Multikine.

  • CEL-SCI initiated the development of an immunotherapy with the potential to treat COVID-19 using the Company’s patented LEAPS peptide technology and signed a collaboration agreement with the University of Georgia (UGA) Center for Vaccines and Immunology to develop its LEAPS COV-19 immunotherapy during fiscal 2020. Following the end of fiscal 2020, in December 2020, CEL-SCI announced that its LEAPS COV-19 peptides, delivered as a therapeutic treatment following SARS-CoV-2 virus challenge, achieved a 40% survival rate in human ACE2 transgenic mouse models as compared to 0% survival in the two control groups in studies conducted at UGA Center for Vaccines and Immunology.

  • The LEAPS platform technology was issued a patent from the European Patent Office titled “Method of Preparation and Composition of Peptide Constructs for Treatment of Rheumatoid Arthritis”. In addition to the treatment of COVID-19, the LEAPS platform technology is being developed as a potential therapeutic vaccine for rheumatoid arthritis supported by grants from the U.S. National Institutes of Health (NIH).

  • CEL-SCI raised net proceeds of approximately $25.8 million during fiscal 2020 through the sale of common stock and the exercise of warrants and options. In December 2020, following the end of the 2020 fiscal year, CEL-SCI raised an additional $14.7 million.

“The aim of our Phase 3 pivotal study is to show that our immunotherapy Multikine can help head and neck cancer patients when administered right after diagnosis, before surgery, radio and chemotherapy have weakened the immune system. After a decade of running the world’s largest Phase 3 study in head and neck cancer, we are looking forward to hearing the final study results which will hopefully prove our concept. We are grateful to all the stakeholders who have patiently been on this long journey with us,” stated CEL-SCI CEO, Geert Kersten.

“While Multikine in the treatment of head and neck cancer is our immediate focus and opportunity, based on Phase 3 results, we may evaluate Multikine for the treatment of other cancers, concurrent with advancing our LEAPS therapeutic vaccine platform in COVID-19 and rheumatoid arthritis,” Kersten concluded.

CEL-SCI reported a net loss of $30.3 million in fiscal year 2020 versus a net loss of $22.1 million in fiscal year 2019. The increase in net loss was predominantly due to an increase in research and development expenses by approximately $5.2 million, or 41%, and an increase in general and administrative expenses by approximately $3.7 million, or 46%, compared to the year ended September 30, 2019.

CEL-SCI believes that boosting a patient’s immune system while it is still intact should provide the greatest possible impact on survival. Therefore, in the Phase 3 study CEL-SCI treated patients who are newly diagnosed with advanced primary squamous cell carcinoma of the head and neck with the investigational product Multikine* first, BEFORE they received surgery, radiation and/or chemotherapy. This approach is unique. Most other cancer immunotherapies are administered only after conventional therapies have been tried and/or failed. Multikine (Leukocyte Interleukin, Injection), has received Orphan Drug designation from the FDA for the neoadjuvant therapy in patients with squamous cell carcinoma (cancer) of the head and neck.

CEL-SCI believes that this Phase 3 study is the largest Phase 3 study in the world for the treatment of head and neck cancer. Per the study’s protocol, newly diagnosed patients with advanced primary squamous cell carcinoma of the head and neck were treated with the Multikine treatment regimen right after diagnosis and prior to receiving the Standard of Care (SOC), which involves surgery, radiation or concurrent radiochemotherapy. Multikine is designed to help the immune system “see” the tumor at a time when the immune system is still relatively intact and thereby thought to better be able to mount an attack on the tumor. The aim of treatment with Multikine is to boost the body’s immune system prior to SOC to attack the cancer. The Phase 3 study is fully enrolled with 928 patients and the last patient was treated in September 2016. To prove an overall survival benefit, the study requires CEL-SCI to wait until 298 events have occurred among the two main comparator groups. This study milestone occurred in late April 2020. The study is currently in the statistical analysis phase.

The Company’s LEAPS technology is being developed for rheumatoid arthritis and as a potential treatment for COVID-19 infection. The Company has operations in Vienna, Virginia, and near/in Baltimore, Maryland.

The Company’s audited financial statements contained an audit opinion from its independent registered public accounting firm that included an explanatory paragraph related to the Company’s ability to continue as a going concern.

Forward-Looking Statements

This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. When used in this press release, the words “intends,” “believes,” “anticipated,” “plans” and “expects,” and similar expressions, are intended to identify forward-looking statements. Such statements are subject to risks and uncertainties that could cause actual results to differ materially from those projected. Such statements include, but are not limited to, statements about the terms, expected proceeds, use of proceeds and closing of the offering. Factors that could cause or contribute to such differences include, an inability to duplicate the clinical results demonstrated in clinical studies, timely development of any potential products that can be shown to be safe and effective, receiving necessary regulatory approvals, difficulties in manufacturing any of the Company’s potential products, inability to raise the necessary capital and the risk factors set forth from time to time in CEL-SCI’s filings with the Securities and Exchange Commission, including but not limited to its report on Form 10-K for the year ended September 30, 2020. The Company undertakes no obligation to publicly release the result of any revision to these forward-looking statements which may be made to reflect the events or circumstances after the date hereof or to reflect the occurrence of unanticipated events.

* Multikine (Leukocyte Interleukin, Injection) is the trademark that CEL-SCI has registered for this investigational therapy, and this proprietary name is subject to FDA review in connection with the Company’s future anticipated regulatory submission for approval. Multikine has not been licensed or approved for sale, barter or exchange by the FDA or any other regulatory agency. Similarly, its safety or efficacy has not been established for any use. Moreover, no definitive conclusions can be drawn from the early-phase, clinical-trials data involving the investigational therapy Multikine. Further research is required, and early-phase clinical trial results must be confirmed in the Phase 3 clinical trial of this investigational therapy that is in progress.


































 

CEL-SCI CORPORATION

STATEMENTS OF OPERATIONS

YEARS ENDED SEPTEMBER 30, 2020 and 2019

         
   

 

2020

 

 

 

2019

 

         

Grant income

 

$

558,664

 

 

$

462,754

 

         

Operating expenses:

       

Research and development

 

 

17,840,290

 

 

 

12,659,287

 

General and administrative

 

 

11,703,429

 

 

 

7,998,573

 

Total operating expenses

 

 

29,543,719

 

 

 

20,657,860

 

         

Operating loss

 

 

(28,985,055

)

 

 

(20,195,106

)

         

Other income

 

 

38,763

 

 

 

73,022

 

Loss on derivative instruments

 

 

(349,078

)

 

 

(760,603

)

Warrant inducement expense

 

 

(805,753

)

 

 

 

Other non-operating gain

 

 

887,604

 

 

 

545,528

 

Interest expense, net

 

 

(1,041,725

)

 

 

(1,797,481

)

Net loss

 

 

(30,255,244

)

 

 

(22,134,640

)

         

Modification of warrants

 

 

(21,734

)

 

 

 

   

 

 

 

Net loss available to common shareholders

 

$

(30,276,978

)

 

$

(22,134,640

)

         

Net loss per common share, basic and diluted

 

$

(0.82

)

 

$

(0.71

)

         

Weighted average common shares outstanding, basic and diluted

 

 

36,759,115

 

 

 

31,174,394

 

         

 

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