Staff organize COVID-19 test packets at the Sanderford Road Park COVID-19 testing site on Tuesday, January 19, 2021 in Raleigh, NC.

Is it better to get immunity from COVID or vaccines?

  • June 17, 2021

Staff organize COVID-19 test packets at the Sanderford Road Park COVID-19 testing site on Tuesday, January 19, 2021 in Raleigh, NC.

Staff organize COVID-19 test packets at the Sanderford Road Park COVID-19 testing site on Tuesday, January 19, 2021 in Raleigh, NC.

rwillett@newsobserver.com

Research shows both coronavirus infection and vaccination offers immunity that can protect people from getting sick again. But by how much and for how long remains unclear — a scientific gap that only time could fill.

Regardless of how immunity is acquired, there’s no telling whose bodies will or won’t create effective antibodies, and why they last longer for some than others; doctors speculate age or certain medical conditions might play a role.

It also doesn’t help that the testing shortage that plagued the nation at the beginning of the pandemic will forever shield researchers from understanding the true impact of COVID-19.

The Centers for Disease Control and Prevention estimates that between February 2020 and March 2021, there were about 114.6 million total coronavirus infections in the U.S.. That’s about 81.1 million more cases than are confirmed as of June 17.

While people can gain immunity from both infection and vaccination, antibodies created from both routes target different parts of the virus, which leads to variations in the quality of protection.

It’s like a coin flip: risk contracting COVID-19 — and potentially becoming a long-hauler — or getting vaccinated. Some argue the final outcome is similar, but one is far more dangerous than the other.

Here’s what the latest data show about immunity from prior infection and vaccines.

Natural immunity from coronavirus infection

There are certain illnesses in which infection can offer more protection than a vaccine.

For example, coming down with measles or mumps is said to confer lifelong immunity to the virus, but some people who get the vaccine may still get infected, although the shots still limit and prevent the spread of outbreaks.

But if the novel coronavirus is anything like others in the coronavirus family, like the Middle East Respiratory Syndrome (MERS), then permanent protection after infection is unlikely.

Studies offer some positive clues, however.

Research published in February found that coronavirus patients gained “substantial immune memory” that involved all four major parts of the immune system: memory B cells, antibodies, memory CD4+ T cells and memory CD8+ T cells.

This protection lasted about six months after infection in most people, but for some, it remained for up to eight months, suggesting it could last even longer in some cases.

Separate research posted in April showed a history of COVID-19 among U.K. patients was associated with an 84% lower risk of reinfection for about seven months after testing positive.

Another non-peer reviewed study published in June found that over five months, 1,359 American health care workers who previously had COVID-19 and didn’t get vaccinated stayed clear of reinfection. The Cleveland Clinic researchers said, in the context of a short supply of vaccines globally, “a practical and useful message would be to consider symptomatic COVID-19 to be as good as having received a vaccine,” adding that people who’ve had the coronavirus “are unlikely to benefit from COVID-19 vaccination.”

While scientists cannot predict who will develop natural immunity, evidence shows people who had severe COVID-19 are more likely to develop a stronger immune response than those who had milder forms of the disease.

Immunity from COVID-19 vaccines

It’s also true that research shows COVID-19 vaccines offer protection against reinfection, although “breakthrough cases” can occur because no vaccine is 100% effective.

However, studies have found vaccine-derived antibodies are more robust compared to those from natural infection — and the job is done without causing illness or other long-term complications often brought on by the disease.

Two doctors from Italy compared the process of infection and vaccination in relation to variants to the plot of an action movie.

It “begins with a character (the virus) running freely across the globe, eluding capture until being finally sent to jail (built by natural immunity). However, if this prison is not secure enough, the virus could escape, aided by certain mutations,” Dr. Emanuele Andreano and Dr. Rino Rappuoli of the Monoclonal Antibody Discovery Lab, wrote in Nature. “Vaccine-induced immunity… should help ensure those escape routes are securely closed.”

An April study that has not been peer-reviewed found that two doses of either the Pfizer or Moderna vaccines offered 10 times higher levels of antibodies compared to those developed after natural infection.

Another April paper showed that people who were previously infected with the coronavirus experienced significant boosts in their preexisting antibodies after two doses of the Pfizer vaccine, which also offered protection against coronavirus variants.

“Vaccines actually, at least with regard to SARS-CoV-2, can do better than nature… They are better than the traditional response you get from natural infection,” White House chief medical adviser Dr. Anthony Fauci said during a COVID-19 briefing in May.

Exactly why vaccines appear to generate more robust immunity than natural infection remains unclear, but Dr. Sabra Klein, a virologist and professor of immunology at Johns Hopkins Bloomberg School of Public Health, said infection and vaccination work in different ways.

“The immune system of people who have been infected has been trained to target all these different parts of the virus called antigens. You’d think that would provide the strongest immunity, but it doesn’t,” Klein said. “The Pfizer or Moderna vaccines target just the spike protein — the part of the virus that is essential for invading cells.

“It’s like a big red button sitting on the surface of the virus. It’s really sticking out there, and it’s what our immune system sees most easily,” she continued. “By focusing on this one big antigen, it’s like you’re making our immune system put blinders on and only be able to see that one piece of the virus.”

In other words, vaccines work to strengthen immune responses gained during natural infection; that’s why health experts advise people who’ve had COVID-19 to still get vaccinated.

“There’s nothing deleterious about getting a boost to an immune response that you’ve had before,” Dr. Marion Pepper, an immunologist at the University of Washington in Seattle, told The New York Times. “You could get an actually even better immune response by boosting whatever immunity you had from the first infection by a vaccine.”

Follow more of our reporting on Full coverage of coronavirus in Washington


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Katie Camero is a McClatchy National Real-Time Science reporter based in Miami. She’s an alumna of Boston University and has reported for the Wall Street Journal, Science, and The Boston Globe.

Giloy powder: Herbal immunity booster for better health & digestion | Most Searched Products

Giloy powder: Herbal immunity booster for better health & digestion | Most Searched Products

  • June 17, 2021
When you are looking for herbal immunity boosters, giloy and its supplements are quite popular in India. Giloy is not just used for reducing fever but is even a great choice for strengthening the immune system, keeping a check on blood pressure and sugar levels, improving metabolism, promoting healthy digestion and more. If you do not want to go for giloy juice, tablets or capsules, you can even take this immunity booster in the form of giloy powder.

Focus on your immune system and take the help of one of these packs of giloy powder that you can buy online. Have a look at this list of some of the most popular options that are worth your money and improve your overall health using natural products.

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If you are finding it hard to prepare kadha or other immunity booster drinks using giloy stem, you can take the help of this pack of stem powder. This organic powder is easy to add to the diet and can be used in multiple ways. Besides boosting immunity, it can help your body detox, reduce mental and physical stress and even reduce anxiety to an extent.

You can have this giloy powder with warm milk or water. The shelf life of this pack is 24 months from the date of manufacturing if you store it well.


In the market of healthcare supplements and products, Baidyanath has been a trusted name in India for years. This giloy powder by the brand is a great immunity booster and even helps in eliminating stomach disorders. So, your digestive system will stay healthy and the food that you take is digested properly.

You can take 1-2 spoons of this powder with lukewarm water as directed by your physician to see a visible difference in your overall health in a few days. Regular consumption of this powder can even keep minor seasonal infections away.


This pack of giloy powder can be another good option to consider buying online for your overall health and immunity. This powder is sourced from forests and is organic. So, you need not think too much before adding this herbal immunity booster to your diet plan. This powder is free from harmful preservatives and additives to ensure that the goodness of giloy is not reduced.

You can boil this powder in water along with tulsi and other herbal ingredients to make your immunity booster drink whenever you want.


This pack of giloy powder can be another affordable choice to consider for your immune system and overall health. This powder is made from the leaves of the giloy plant and can even help you reduce stress and anxiety to an extent. So, you can use it as an immunity booster and stress-buster.

Store this giloy powder in an airtight container to avoid the loss of nutrients or contamination due to exposure to dust, moisture or pollutants.


This giloy powder can be another affordable immunity booster that you can buy online. This powder is made from the stem of the giloy plant to give you plenty of nutrients and allow you to prepare various immunity booster drinks easily at home. Available in a zip-lock pouch, it is easy to store this giloy powder at home.

You can have 1 spoon of powder with water as per the instructions of your doctor to boost your immunity.

Get it here.



Look for other options in giloy powder here.

DISCLAIMER: The Times of India’s journalists were not involved in the production of this article.

3 COVID shots could boost immunity in solid organ transplant recipients

3 COVID shots could boost immunity in solid organ transplant recipients

  • June 17, 2021

BIRMINGHAM, Ala. (WBRC) – New research from Johns Hopkins University Hospital shows a third dose of the COVID-19 vaccine could be a way to improve immunity in immunocompromised patients, especially for organ transplant recipients.

Health experts said solid organ transplant recipients tend to have weakened immune systems.

“When you have an organ transplant, you get put on very powerful drugs to suppress your immune system because it’s your immune system that can otherwise lead you to reject those organs that you’ve received, and therefore when they’re given a vaccination, the vaccine doesn’t induce immunity. It doesn’t create an immune response,” said State Health Officer for the Alabama Department of Public Health, Dr. Scott Harris.

But a new study from Johns Hopkins University Hospital shows a third dose of the COVID-19 vaccine could improve immunity response in these groups.

“We’ve had these people with immune system problems like organ transplant patients who are allowed to take a vaccine, but whom we really didn’t expect the vaccine to work, and so, it’s encouraging to that perhaps there is a way to induce immunity in these patients,” Dr. Harris said.

The study followed 30 solid organ transplant recipients.

Almost all of them had low or no immunity to the vaccine.

But after a third shot, 33% of patients with no immunity, and 100% of patients with low immunity, increased their antibody levels.

“We also know that because of their medical conditions, in many cases, they’re at even more risk of serious illness if they do get COVID compared with the average person. We want to protect them even more, in a way, than the average person. So, it’s encouraging to think that we may have a way to do that,” Dr. Harris said.

Health experts said this 30-patient study isn’t big enough to be a formal patient trial, but it’s enough preliminary data to show promise in future studies.

They still recommend organ transplant recipients get the vaccine, but still take precautionary measures to ensure protection.

Copyright 2021 WBRC. All rights reserved.

Florida News Times

Third dose of COVID vaccine may boost immunity of transplant recipients-WUSF public media

  • June 16, 2021

Pharmacist Katie McDonough reconfigures the Pfizer-BioNTech vaccine when filling syringes at the UMass Memorial Healthcare COVID-19 Vaccination Center at the Mercantir Center in Worcester on April 22, 2021. Joseph Prezioso AFP

A small new study offers a faint hope that organ transplant recipients can be given a third dose of the COVID-19 vaccine to enhance their defense against coronavirus.

It’s important Previous studies show Almost half of organ transplant recipients showed no antibody response after two doses of Pfizer or modelna vaccine.

And even transplant recipients who responded antibody to vaccination were often more modest than those with a healthy immune system. Therefore, doctors advise these patients not to assume that vaccination is equivalent to immunity. According to the Scientific Registry of Transplant Recipients, more than 400,000 people in the United States have undergone organ transplants.

In a new study Published this week Annual report of internal medicineResearchers at Johns Hopkins University of Medicine tracked 30 organ transplant recipients who received a third dose of the COVID-19 vaccine.

They found that one-third of patients who did not have previously detectable antibodies showed increased antibody levels after the third dose. And all patients who previously showed low levels of antibody after two doses of vaccine showed high levels of antibody after the third dose.

“For everyone involved [these are] A promising finding that the defensive immunity of immunosuppressed people may ultimately be reached, “said Dr. Dolly Segev, a transplant surgeon and study author at Johns Hopkins Medicine... Although the findings are preliminary, he says, they are consistent with previous studies of how transplant recipients respond to other vaccines.

Researchers say this is the first study to report a response to a third vaccination. In this observational study, they tracked group transplant recipients who asked for a third dose on their own and tested antibody levels after dosing.

Researchers say their findings support the use of clinical trials to determine whether transplant recipients should receive the COVID-19 vaccine booster as part of standard clinical care. If the findings are reproduced in a larger study, they may affect some other types of immunocompromised patients.In fact, in France Health officials already recommend Patients with severe immunodeficiency, such as organ transplant patients and dialysis patients, receive a third dose of Pfizer or modelna vaccine.

Segev says he expects more data from France to come from France regarding the effectiveness of a third dose in immunocompromised patients.

“Obviously, all we need to learn is … who responds to the third dose,” he says. “People who need changes other than the third dose,” such as temporary changes in immunosuppressive drugs to improve the antibody response to vaccination.

Segev and his colleagues are currently seeking regulatory approval to give transplant recipients a third dose of the vaccine and initiate an intervention study that can monitor their response. They hope to be able to register participants next month or two months.

But for now, “the best we can all do for immunosuppressed people is that our normal immune system can protect vulnerable friends and family among us who have suppressed the immune system. So, get all the vaccinations, “he says.

Third dose of COVID vaccine may boost immunity of transplant recipients-WUSF public media

Source link Third dose of COVID vaccine may boost immunity of transplant recipients-WUSF public media

How To Use Giloy To Boost Your Immunity, Reduce Fever & More? | Most Searched Products

How To Use Giloy To Boost Your Immunity, Reduce Fever & More? | Most Searched Products

  • June 16, 2021
Giloy or Tinospora Cordifolia is a medical plant belonging to herbal vines that grow in the tropical regions of the Indian subcontinent. Giloy has been used for centuries in India and around the world to treat various ailments.
In Ayurveda, Giloy is considered to be one of the best medicines to control and reduce various fevers and other ailments. Giloy has been called an ‘Amrit’ or Immortal plant in Ayurveda because of its high immune-boosting and other medicinal properties.
Before understanding how to use giloy to boost your immunity, it is important to understand the medicinal properties of this plant.

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Medicinal properties of Giloy
Giloy is effective against ailments such as diabetes, neurological problems, fevers such as hay fever, dengue fever, and chronic fever. The giloy plant also helps people in lowering their anxiety and stress levels by cleaning the body from toxins.
The stem of giloy plants is considered to have the most nutritional value. It is advised to take giloy in powdered form or in the form of kadha (decoction) or even juice. The dosage of giloy would depend on the level of ailment.

How to make giloy juice at home?
Get some freshly cut stems of the giloy plant and blend them well with water in a blending machine to obtain giloy paste. Dilute the paste and sieve it to obtain giloy juice. The juice should be consumed as per your general physician’s advice. Giloy can also be taken in powdered form and tablets

Here is a guide for you on how to use giloy to boost your immunity.

Uses of Giloy
  • Anxiety and Stress Reliever

Using Giloy for boosting immunity

Giloy herb is rich in alkaloids, glycosides, steroids, and other compounds that activate the immune system and increase vitality in a person. To boost your immunity, mix it with a small amount of water, you can refer to your general physician about the required dosage. It is advisable to take giloy juice twice daily before meals.

This giloy juice is added with neem and tulsi that are known for their antimicrobial properties and medicinal properties respectively. Giloy and neem together cleanse the liver which is responsible for getting rid of toxins from your body. This juice can be consumed twice a day before meals or as advised by your physician. Tulsi furthers cleanses and rebuilds cells of the body.

Get more Giloy Juice Here:

Using Giloy for reducing fever

Giloy can be used in the treatment of various fevers including chronic, dengue, malaria, and hay fevers. Fever generally happens due to two reasons – remaining toxins in the body from food and water or due to the entrance of foreign pathogens.

Giloy is rich in javarghana which has properties to fight and reduce fever. Similarly, giloy has anti-inflammatory properties that attack the cause of the fever and helps the body retain normal temperature.

To reduce fever, one can be given giloy juice or giloy kadha. Alternative use could be to mix giloy powder with few drops of honey and have it as advised by the doctor.

This giloy powder helps in correcting imbalances in the body that lead to problems such as burning sensation of hand and feet, allergy, skin inflammation, and acidity. The powder is directly obtained from the giloy plant and has no added preservatives. Use the powder with water or honey for best results

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Using Giloy for controlling blood sugar levels

Giloy enhances the production of insulin in the body, insulin controls the level of sugar in the body. High sugar levels can lead to ulcers and kidney problems. Use giloy powder with half a glass of warm water in the morning and at night.

This is a pack of 60 vegetarian capsules that can be consumed twice as per the instructions of your doctor. These capsules can be taken with warm water in the morning or at night, as advised by your doctor. Giloy capsules also help in liver function by regulating enzymes and metabolism.

Buy more Giloy tablets here:

Buy Neem Juice Here

Use Giloy for Improving Digestion

Giloy regulates metabolism in the body that aids the entire food eating and digestion process. It is useful in treating acidity, vomiting, colitis, and various other problems such as nausea, diarrhea.

You can take half a spoon of giloy juice with half a glass of lukewarm water in the morning and at night to reduce stomach and gut-related ailments.

Use Giloy for anxiety and stress relieving

Giloy is also used to treat anxiety and stress. The plant contains antioxidants that clear the body of toxins, it calms down your body and mind as well. The herbal plant also improves the cognitive behavior of the person. Use half a spoon of the giloy juice with the same amount of water on an empty stomach in the morning to have a peaceful and anxiety-free day.
If you have anxiety then the below-mentioned guide can be referred to help in anxiety and stress relief at home.

Learn more on how to relieve stress and anxiety at home:
Buy stress relievers here:
Buy Essential oils for relieving stress here:

If you are interested in knowing how other medicinal plants can help you have a better lifestyle then refer to the guide below.

Here is how aloe vera can cure your skin and hair problems:

Other FAQs

  1. Can five-year-old children be given giloy juice?
    Yes, it can be given to five-year-old children upon the advice of the doctor.
  2. What is better- giloy juice and powder or tablets?
    If you are looking for instant giloy usage then giloy juice and powder are better. However, if you are looking for long-term usage of giloy then it is advisable to consume giloy tablets.
  3. Is giloy good for hair?
    Yes, giloy contains antioxidants properties that are good for hair strength and scalp care.

DISCLAIMER: The Times of India’s journalists were not involved in the production of this article.

Covid immunity lasts for a year, vaccine boost helps fight variants, study says

Covid immunity lasts for a year, vaccine boost helps fight variants, study says

  • June 16, 2021
Covid-19 vaccine shot | Representational image | Bloomberg


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New Delhi: Immunity in Covid-recovered patients is long-lasting and gets a 50-fold boost after vaccination, according to a new study.

The study, published in the journal Nature Monday, also said that the mRNA vaccines can sufficiently protect against emerging mutations.

More than a year after the Covid-19 pandemic broke, the emergence of new variants that appear to be more transmissible and resistant to antibodies has added to the challenge of controlling the spread of the disease.

To understand how long the immunity lasts, researchers from the Rockefeller University, Weill Cornell Medicine and California Institute of Technology assessed the blood samples of 63 people who had recovered from Covid-19. The samples were collected 1.3, 6.2 and 12 months after infection.

Of these 63 people, 41 per cent had received mRNA vaccines.

The study found that in Covid-recovered patients, antibodies against the protein known as receptor binding domain (RBD) of SARS-CoV-2 and neutralising activity remain relatively stable from six to 12 months, without vaccination.

A receptor-binding domain is a key part of the virus located on its ‘spike’ protein that allows it to latch onto the cell to gain entry into cells and lead to infection.

Memory B cells — a type of white blood cells that learn to recognise specific viral proteins — was also found to remain stable upto 12 months.


Also read: New atomic-scale 3D map of Covid virus protein could hold clue to preventing lung damage


Antibody levels

In addition, the team found that vaccination increases all components of the antibody response. Antibody levels remained relatively unchanged between six to 12 months after SARS-CoV-2 infection, and that vaccination further boosted this activity by nearly 50-fold.

The study found that the ability of vaccine-induced antibodies to neutralise variants of concern was comparable to or greater than that against the original virus.

Researchers also identified that the broad response against the SARS-CoV-2 virus involves what is known as the antibody somatic mutation — a cellular mechanism using which the body’s immune system adapts to the changing virus during the course of the infection.

This results in antibodies that are exceptionally resistant to mutations in the SARS-CoV-2 RBD — including those found in variants of concern

In addition, B cells that produce a broad range of potent antibodies are retained in the body over time and expand dramatically after vaccination.

The data suggest that immunity in Covid-recovered individuals will be very long-lasting, researchers said. Along with this, Covid-recovered patients who receive mRNA vaccines produce antibodies and memory B cells that should be protective against circulating SARS-CoV-2 variants, the study concluded.

(Edited by Neha Mahajan)


Also read: AY.1 — The new Covid variant on world radar stems from Delta variant, linked to immune escape


 

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